60 year old man with history of chronic low-grade depression. One year bout of major depression, chronic back pain (lower and upper), degenerative spinal cord arthritis. Thready pulse, kidney qi deficient, liver qi stagnation. Slightly flabby tongue with red tip, purple center, raised on center line. Taking St. John’s Wort, 5HTP, SAMe for pain and Zizyphus 18 to help with sleep. Want to address morning lethargy and despondency.

Griffonex 5-HTP is more for anxiety, okay to use before bed. With regard to SAMe, you might want to increase the dosage. Might consider Backbone. If Backbone is too warming, consider Astra Essence. 

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